Publications
Science
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Analysis
Over 30,000 unique patients participate in studies.
For each module, there is a scientific governance working group. This ensures that:
1. data are anonymised;
2. persons must have given their consent.
The Oracle database always exports data in the same way.
Summary
All available publications via Curavista are rendered per year.
The main message is summarized for a broad audience.
For scientific purposes, we recommend you to read the articles. The links are provided and are open access.
2024
Detection of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease using home monitoring in the Netherlands (DecreaSSc).
A prospective, observational study.
Experiences of systemic sclerosis patients with home monitoring of their pulmonary function.
A qualitative study.
Patient satisfaction
Telemonitoring via Gezondheidsmeter can also be applied to less well-known and small patient groups such as Systemic Sclerosis. With high patient satisfaction.
The ABCC-tool, Assessment of the Burden of Chronic Condtions will be implemented in Italy.
The aim is to relieve GP practices in caring for the chronically ill. This study will evaluate the effectiveness of the Dutch ABCC-tool for four Chronic Conditions (DM2, Heart Failure, Asthma, COPD) when deployed in GP practices in South Tyrol. Study protocol description. The ABCC-tool is developed by the Caphri Instittute of Maastricht, Netherlands.
2023
Spirometry@home, experiences in 9 Dutch hospitals
During the Corona pandemic 300+ patients received a handheld Bluetooth® spirometer per postal services. The easy to use software of Gezondheidsmeter showed that home monitoring is very feasible in a regular care setting.
Vertigo Training as effective as a GP consultation
Vestibular rehabilitation (targeted exercises) is a safe and effective way in the treatment of chronic vestibular symptomem (dizziness). However, treatment is not widely used in daily general practice. Therefore, an online self-training programme was developed. This training is as effective as a consultation.
Drug Rediscovery: thioguanine in IBD
This research shows that thoguanine is a much cheaper alternative to anti-TF-alfa inhibitors. Patients with Inflammatory Bowel Diseases remained in clinical remission without using corticosteroids over a 12-month period on monotherapy thioguanine. 80% of patients continued using thioguanine. Together with positive PGA and quality of life scores, this highlights the efficacy and tolerability of thioguanine in IBD.
Drug Rediscovery: process description registration thioguanine in IBD
Drug rediscovery aimes to rediscover well known drugs to new indications. What hurdles to overcome and why is it useful and necessary? An overview of the registration process of thioguanine in the Netherlands, where Health Meter collected the data for 2 studies.
Spirometry@home international
This study measures the change in FVC in patients with Pulmonary Fibrosis (PF) using the Spirobank Smart. A large number of international hospitals are collaborating in this. In addition, the outcomes measured with questionnaires (PROMS) are investigated in different subgroups of patients with PF. More information on the study website https://www.i-file.app
Spirometry: independent use by patients
During the Corona pandemic, patients could not come to the hospital for instructions. This study analyses the results of 373 patients, who started completely independently and blew and transmitted lung functions online for a long period of time. Doctors signed patients up, the helpdesk sent spirometers by mail with simple instructions. Telephone instructions were possible. The home measurement results did not differ from regular results.
2022
Telemonitoring vs Regular Care
The goal of MSmonitor with video consultation that that people with MS gain a better understanding of the individual disease course and more control over their symptoms. This knowledge should increase autonomy and give people more control over their disease and allow them to better interact with healthcare professionals. This makes the consultation more efficient, MS-related problems are detected earlier, multidisciplinary care can be organised earlier, and treatment can be adjusted more quickly. This can have a positive effect on the quality of life for the person with MS and his/her partner and informal carer, thus saving costs of care and the social domain.
Telemonitoring at Post-Covid with lung function home blowing
Six months after discharge from hospital for COVID-19 treatment, lung function and quality of life still improve, but fatigue remains. Home monitoring allows detailed follow-up of patients with COVID-19 with low burden on patients and care.
Telemonitoring in Post-Covid
In the first 6 months after discharge from hospital for COVID-19, most patients recover in many domains, but recurrent fatigue occurs regularly. Fatigue has a strong impact on quality of life.
Simplicity in PROMs
VAS scores correlate with validated PROMs in IPF and are also reproducible. Because VAS scales are so simple, they potentially offer great value in systematic evaluation of disease progression in research and regular care.
Post-Covid Profiling
12% of people reported substantial symptoms after 1 year and were considered post-COVID. The majority (60%) reported an increase in symptoms. In addition, obesity and lack of physical activity seem to be risk factors. No associations were found with gender or age.
2021
Cost-effectiveness
App-based treatment is a viable alternative to care-as-usual for UI in primary care in terms of effectiveness after 1 year.
High Adherence and Satisfaction: home spirometers
Blowing lung function at home and forwarding it online (home monitoring) is quite feasible in patients with SSc-ILD. There is high adherence and satisfaction. Larger studies are needed to determine whether home triometry can also identify progression of ILD in patients with SSC.
Post-Covid Measuring tool: disease burden meter ABCoV
Developing the ABCoV-19 / Disease Burden Meter post-Covid: usability for people.
Transmural Collaboration: case manager & PBM
Transmural collaboration can be via the online Personal File (PBM) This development requires more research, due to the high failure rate. A coordinating case manager as a focal point in this personal digital environment could add value. Another possibility is to offer a financial incentive to GPs, specific education and more focus on using the PBM in managing care.
Hybrid Care is Effective
COPD patients are more likely to use the platform in a blended care setting compared to COPD patients who use the eHealth platform independently. Blended care seems essential in adherence to eHealth programmes in COPD, and may subsequently lead to better self-management.
2020
Patient Safety: measuring lung function at home
The experience in ErasmusMC is that home measurement of lung function, symptoms, and side effects is safe for regular care care and clinical trials. At the same time, patients are more involved and it encourages self-management.
Online measurement of Minimal Clinical Difference
A change of at least 3.5 points is clinically relevant in patients with SFNSL.
Lung Transplantation and Spirometers
Online home monitoring where data are visible directly to professionals (real-time) is possible and reliable after lung transplantation. The result is high patient satisfaction.
RCT Proves: Personalisation via home monitoring is relevant
Results show from this first eHealth RCT in IPF that a comprehensive home monitoring programme does not improve overall quality of life (measured by the K-BILD) but tended to increase psychological well-being. Home monitoring was highly appreciated by patients and medication was adjusted siginificantly more often in the monitoring group.
When to blow lung function?
It does not matter whether patients blow lung function in the morning or in the evening: the differences in FVC are too small to have an impact on treatment decisions.
Patient Empowerment
Patients with MS using the MSmonitor programme with their caregivers for the first time showed no short-term improvement in empowerment in terms of self-efficacy, self-management, autonomy, or participation. The lack of effect was not due to non-use of the programme.
Medication Setting and Use
Patient experiences and satisfaction with medication treatment are quite positive and similar for nintedanib and pirfenidone. Systematic evaluation of patient expectations, experiences and satisfaction with medication can support "co-decision" and medicinal treatment decisions.
Predmeth: efficacy prednisone vs methotextate in pulmonary sarcoidosis
This study should show which treatment is preferred as first-line treatment in patients with pulmonary srcoidosis. Publication of study protocol.
2019
Multiple Devices and Modules Work Well
A comprehensive home monitoring programme (PROMS, lung function at home, Fitbit) is possible and could be used in sarcoidosis research. Home monitoring may also be attractive for regular care, although studies are needed to demonstrate the added value. the potential of home monitoring is to recognise symptom changes early and adjust treatment accordingly. Especially in a heterogeneous disease like sarcoidosis, home monitoring can lead to personalised treatment, increased self-management, and improved quality of life.
Personal Experience in DM2
The Trigger study provides education and support to people with type 2 diabetes. There was a small but clinically irrelevant difference between the groups. The advice is to make programmes more personal and offer them to people who think an app would be useful for them.
COPD Module Scores Good in Comparison
My copd online (COPD module on Health Meter) scores "green" in this survey of 13 online applications for COPD....
2018
Pain reduction in patients with cancer
By understanding pain patterns, side effects on medication, treatment can be quickly adjusted via online messages and eConsult. This results in a significant reduction in pain within 6 weeks.
Empowerment through combination Disease module and Fitbit
By using the FitBit, the chronically ill experience better health and can better manage their disease.
Personal factors play a role
Personal factors, disease-independent, play an important role in the use of online monitoring programmes in COPD. For expectation management, this factor should be included in implementation in regular care.
Feasible and appreciated, even among the elderly
A home monitoring programme with online lung function bladders, is highly feasible and appreciated by patients with IPF. The real-time changes of FVC and outcomes of PROMs enable personalised care.
2017
eHealth: embedding in mainstream care
In patients with asthma and COPD, adherence to the online monitoring programme was found to be significantly longer when the professional was watching.
Stopping medication
Patients with higher scores on quality of life and self-efficacy prior to self-injection medication were less likely to discontinue medication.
Completion of PROMs
After 2 years, patients appear to complete both the longer and shorter PROMs. The intervals between the longer PROMs are longer than between the shorter PROMs, though.
Can online monitoring in IPF?
Development and applicability of an online monitoring programme with PROMs and progress charts in patients with IPF.
2016
Pain and itching in Herpes Zoster.
Pain mainly has an impact on quality of life. Itching actually doesn't.
2015
Barriers to implementation of eHealth in COPD
Lack of remuneration for the structural application of eHealth in regular care is a barrier for professionals. For patients, ease of use and feedback from the professional are the most important aspects.
Description new registry for neurosarcoidosis.
Neurosarcoidosis is a rare disease. To understand its symptoms and treatment, the registry was launched.
MSmonitor: concept and first results
In the MSmonitor group, MSSES scores remained the same, knowledge increased. Use was high of the various programme components.
MS study: protocol publication
The aim of this study is to measure real-life long-term how people with MS are doing. The study is being analysed and has been running for over 10 years.